دانشمندان برای اولین بار اثرات پودر و عصاره چای ماچا را در کاهش اضطراب در مدل حیوانی نشان دادند. ماچا جایگزین ایمن و طبیعی برای تسکین اضطراب و افزایش خلق و خوی است.
خلق و خو و اضطراب disorders are becoming commonplace in our fast-paced and often stressful lives. اضطراب disorders and fear has been linked to disturbance in dopaminergic and serotonergic systems in our brain. اضطراب symptoms also increases risk of other medical disorders and affects overall wellbeing of a person. Anxiolytic (or antianxiety) agents like benzodiazepines and serotonin inhibitors are generally used for treatment as they reduce or inhibit اضطراب. However, they have many side effects, sometimes even adverse, and they also increase dependency. Safer, natural alternative need to be developed for اضطراب مدیریت.
In Japan, ‘Matcha’ has been used since a long time for different medicinal purposes. Matcha is a finely grounded power of new leaves from tree plant called عصاره چای سیاه و سبز که فقط در سایه اجازه رشد دارد. از پودر ماچا برای ساخت استفاده می شود چای ماتچا by adding it directly to hot water. It is also used for adding flavour to food. Matcha چای is different from regular green tea in its content mainly because of differences cultivation and processing. عصاره چای سیاه و سبز این گیاه سرشار از L-theanine، اپی گالوکاتچین گالات (EGCG)، کافئین، ویتامین ها و اسیدهای آمینه است و بنابراین مصرف ماچا مزایای متعددی را به این مواد فعال زیستی متصل می کند. معمولاً در ژاپن برای درمان، آرامش و حتی درمان بیماری های پوستی استفاده می شود. با این حال، شواهد علمی بسیار محدودی برای حمایت از ادعاهای فوق در دسترس است. همچنین، اثرات پودر ماچا بر جنبه های رفتاری تاکنون مورد بررسی قرار نگرفته است.
یک مطالعه منتشر شده در مجله غذایی کاربردی has investigated and demonstrated the effects of Matcha چای powder, hot water extract and ethanol extract for ضد اضطراب activity in an animal model (here, mice). Researchers conducted an elevated plus maze (EPM) test in healthy animals. EPM involves use of an elevated plus-shaped platform which has two open arms and two closed arms with walls around it. It is a commonly used anxiety test in which animal subjects which are anxious try to stay on the safe area of the plus where they cannot fall off.
The animals were orally administered Matcha powder and extract or fractions dissolved in water. Results showed that the animals who had consumed Matcha had reduced اضطراب. The strongest effect was seen in Matcha extract derived using 80% ethanol when compared to extract derived from hot water. This meant that poor water-solubility of Matcha has better ضد اضطراب effect than when it was easily water soluble. The ethanol extract was fractioned further into hexane soluble, ethyl acetate soluble and water-soluble fractions which exhibited similar results. Behavioural analysis showed that Matcha power and extract reduce اضطراب by activating dopamine D1 and serotonin 5-HT1A receptors which are closely linked to anxious behaviour.
The current study conducted on mice demonstrates that Matcha چای powder and extract have a positive calming effect and reduce anxiety by activating dopaminergic and serotonergic systems in the brain. Matcha is a safe and natural alternative for alleviating anxiety.
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منبع (ها)
Kurauchi, Y. et al. 2019. Anxiolytic activities of Matcha چای powder, extracts, and fractions in mice: Contribution of dopamine D1 receptor- and serotonin 5-HT1A receptor-mediated mechanisms. Journal of Functional Foods. https://doi.org/10.1016/j.jff.2019.05.046
